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For instance, administering IGF-1R mAbs in cancer trials was reported to result in increased adverse events in younger populations 34 , including insulin resistance, possibly due in part to disruption of the somatotropic axis and associated deleterious effects of excess GH 41,42

Role of CCAAT enhancer-binding protein beta in the thyroid hormone and cAMP induction of phosphoenolpyruvate carboxykinase gene transcription

Organ, C

While iron metabolism and lipid peroxidation trigger ferroptosis under pathological conditions, the precise mechanisms remain incompletely understood and warrant further investigation

Burns 2010;36(4):581584

Alterations in the testis of hormone sensitive lipase-deficient mice is associated with decreased sperm counts, sperm motility, and fertility