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Mol Med 29 , 132 (2023)

Indole acetic acid has been shown to be an important ligand for the aromatic hydrocarbon receptor (AhR), a ligand-activated transcription factor involved in the expression of enzymes that metabolize xenobiotics, inflammatory cytokines and adhesion molecules, all of which are mediators of inflammation in cardiovascular diseases (88)

The 2025 systematic review in orthopaedic sports medicine looked at 35 animal studies and found no lethal dose across multiple administration routes and a wide dosing range (6 g/kg to 20 mg/kg)

Preventing advertisers from saying what a drug is meant to treat may seem like an odd technicality to some after all, the effects of drugs such as Ozempic have been widely publicized

We know it can cause profound personal experiences