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This suppression is the result of components in the extract inhibiting the rate-limiting enzyme of cholesterol biosynthesis HMG-CoA reductase (HMGR) as well as activating the potent metabolic regulatory enzyme AMP-activated kinase (AMPK)

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These findings are consistent with data accessed April 11, 2025

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Second, an in vitro method was used to evaluate the binding affinity of TPT and the selected TPT impurities to different class II HLA-DRs in vitro