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The primary outcome was a composite of worsening heart failure (hospitalization or an urgent visit resulting in intravenous therapy for heart failure) or cardiovascular death

In summary, the accumulation of TMAO will not only increase oxidative stress and endothelial cell damage and permeability but also lead to an increase endothelial-derived NOS expression (56), thereby aggravating disease progression

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In rodents, high PPAR expression has been detected in tissues characterized by a high rate of fatty acid oxidation, including brown adipose tissue, liver, kidney and heart (Escher et al., 2001

Before starting any treatment, a specialist first investigates the cause of male infertility

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