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doi: 10.1016/j.biopsych.2016.12.031 221 DinanTGCryanJF

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These changes increase sensitivity to pain, anxiety, and depression

However, AMPKs effects are context-dependent: under nutrient-replete conditions, AMPK-deficient T cells maintain normal responses, but during glucose restriction or metabolic stress, their adaptability is severely impaired (84)

[DOI] [PubMed] [Google Scholar] 232.Hockel M, Schlenger K, Hockel S, Vaupel P

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