Even though, considering the essentiality of copper in humans, the copper hypothesis of GHK mechanism of action seems very attractive, recent gene data may challenge this mechanism and demand more studies into GHKs mechanism of action
(3) The intestinal microbiota has the capability to convert botanical constituents into secondary metabolites that possess potent pharmacological properties
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Ill leave it to the reader to hypothesise on this
The multi-system interaction framework provides an integrated potential understanding of PEMs complexity, suggesting that future therapeutic strategies may need to simultaneously target energy metabolism, immune regulation, and neuroprotection to effectively help disrupt this pathological cycle
