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The FDA requires that prescribers of semaglutide counsel women that pregnancy is contraindicated during treatment and for two months after discontinuation [8]

In clinical trials, retatrutide has been administered as a once-weekly subcutaneous injection, with a structured dose-escalation schedule used to improve tolerability

I have to listen to my body for other cues that I need to eat, because I can quite happily go out, have a full active day, and not feel the need to eat at all. (P1, male, obesity)

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He said studies like this one werent possible when those drugs first became available, but he thinks the role of big data in getting a wider look at what drugs might do, is important to consider