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While CJC-1295 acts as a GHRH (the accelerator for GH production), Ipamorelin acts as a Ghrelin receptor agonist (the inhibitor of Somatostatin, which usually stops GH release)

This is followed by further phosphorylation of two additional docking tyrosine residues in the carboxy terminal tail (Tyr1349 and Tyr1356) which on activation can act as degenerate motif to recruit several other subsequent signaling molecules

Okumura, C

After the incubation, the samples were run on 6% native polyacrylamide gel containing 0.5Tris-borate-EDTA buffer

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