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Here we report the engineering and preclinical development of a bimodal molecule that integrates NMDA receptor antagonism with glucagon-like peptide-1 (GLP-1) receptor agonism to effectively reverse obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease
Herlev og Gentofte Hospital Steno Diabetes Center Copenhagen Department of Biomedical Sciences Mats Christian Hjbjerg Lassen, MD To view or add a comment, sign in Moderate-to-Vigorous Physical Activity and Cardiovascular Outcomes in Genotype-Positive, Phenotype-Negative Cardiomyopathy Carriers In a large prospective cohort from the UK Biobank including 84,699 individuals, of whom 3,979 were genotype-positive and phenotype-negative (G+P) carriers of cardiomyopathy-associated variants, objectively measured moderate-to-vigorous physical activity (MVPA) was consistently associated with meaningful cardiovascular benefit
Keeping up and questioning is essential as the science and alternatives will continue to evolve
Yes, it improves glycemic control in type 2 diabetes patients
Bacteriostatic water for peptides is crucial in ensuring the stability and efficacy of these substances