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Retatrutide is expected to be a blockbuster in weight loss treatment due to its unique mechanism of action

Possibly higher-impact cardio such as jogging or interval work can begin later if it is not painful in treated areas

At minimum, the marketing claims significantly overstate the likely benefits

Tirzepatide once weekly for the treatment of obesity. NEJM , 2022

Certain side effects are common when using GLP-1s, like fatigue, nausea, constipation, muscle loss, hair loss, or weakness

Retatrutides triple agonist action could account for why in human clinical trials, it has led to more weight loss than older medications