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Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)
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doi: 10.1039/C5CS00878F 135 GuanXChenFFangQQiuS
LiNWenLWangFWangTLiTQiaoMet alMechanism of mitigating effect of wheat germ peptides on lead-induced oxidative damage in PC12 cells
Gesek and Schoolwerth, 1991
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