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CD8 + cytotoxic T lymphocytes, reactive to TPO and Tg, promote glandular destruction, aided by increased ICAM-1 expression on follicular cells and elevated serum levels of VCAM-1 and TIMP-1

1 2 European Journal of Internal Medicine

However, the loss of eGFR was still in the range of what we would now consider rapid progression [47]

Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Most common side effects: nausea, vomiting, diarrhea, constipation, dyspepsia

Treatment suitability, dosing, and results vary by patient