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It was first formally described in the scientific literature in 1993 by a team of researchers led by Sikiric and colleagues

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IL-1R, IL-1, IL-6R, IL-6 a , IL-2, IL-10, IL-15, IL-17, IL-17R, IL-18, IL-23, interleukin (IL)-1 receptor, -1 beta, -6 receptor, -6 antibody, -2, -10, -15, -17, -17 receptor, -18, -23, respectively