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Carrington PR, Sanusi I, Winder PR, Turk LL, Jones C, Millikan LE

Primary care physicians will likely need education and training focused on this new class of medications, given a shortage of endocrinologists and obesity medicine specialists. Lee and colleagues noted there were study limitations, such as a lack of data on prescription indication, including whether it was used off-label. However, the increase in dispensing of injectable semaglutide for weight management suggests increasing use for this indication, they wrote

In both groups, distress is driven less by weight loss and more by a sudden change in appearance

Isolated vomiting is less common and usually self-limiting within days

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