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A recent study in ATC cells showed that metformin increased NIS mRNA and protein expression (as well as mRNA of thyroglobulin, TSHR, and NKX2.1) acting also as a demethylating agent ( Finally, some studies also showed that metformin could synergize with other drugs increasing their anti-cancer effects

doi: 10.3109/03602532.2016.1157600 153 WeiskirchenRTackeF

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