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Giancaterini A, De Gaetano A, Mingrone G, et al

In: Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA, editors

Studies indicate that patients with lower BMI respond better to biological therapies, potentially because reduced adipose tissue decreases the inflammatory burden and may improve drug pharmacokinetics

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GIPR (glucose-dependent insulinotropic polypeptide) At 1 mg, the GIP signal is already about twice the peak produced by a large meal in obese individuals, and it persists instead of fading. Metabolically healthy bodies respond more strongly

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