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[DOI] [PubMed] [Google Scholar] 16.Wilding J.P.H., Batterham R.L., Calanna S., Davies M., Van Gaal L.F., Lingvay I., McGowan B.M., Rosenstock J., Tran M.T.D., Wadden T.A., et al

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Anorectics, medications designed to suppress appetite, like fen-phen (serotonin releasing agent) were commercialized, but eventually withdrawn from the market (1997) after they were found to cause valvular disease and pulmonary hypertension

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But when combined with GLP-1 and GIP activation, the hyperglycemic effects are neutralized , while the lipid-lowering benefits remain

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