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doi: 10.1172/JCI110335

Who Should Not Use Semaglutide With Acid Reflux

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GLP-1 tells your pancreas to release insulin, but only when your blood sugar is high, which is exactly what you'd want from a diabetes drug

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Conversely, in another study with 10 healthy adults where glucose levels were maintained between 70 80 mg/dL, fat ingestion elicited a fivefold to sixfold rise in GIP levels without concomitant insulin secretion (119)