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SURMOUNT-1 and STEP-1: Obesity-Specific Trials SURMOUNT-1 (Tirzepatide for Obesity, NEJM 2022): At the maximum 15 mg dose, participants without diabetes lost an average of 22.5% of their body weight over 72 weeks approximately 51 lbs for a 225-lb person

Beta-oxidation and beta-3 adrenergic signaling are selectively stimulated, enabling detailed studies of lipid metabolism and energy regulation

The left insula, hypothalamus, and orbitofrontal cortex are involved with reward, food anticipation and satiety, and GLP-1 receptors are found in these areas (5)

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There is no research to support this claim, and it hasnt been reported in clinical trials

All MT-2 components synthesised in the USA via solid-phase methodology and verified at 99%+ purity by HPLC and Mass Spectrometry