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The remarkable effect of GB removal is reflected in changes in the rhythm and intensity of BA flow rather than in the mean hepatic BA output (flux of BA molecules to the intestine per unit time) and the mean BA pool circulation rate

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Effect in skin lightening varies from one person to another

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Despite the promise of GST P1-1 as a therapeutic target and the considerable research effort in developing GST inhibitors, to the best of our knowledge, few have entered clinical studies