[20] Through its role as an HDAC inhibitor, butyrate influences the expression of genes involved in: [27] Mitochondrial function - enhancing cellular energy production Synaptic plasticity - supporting learning and memory formation Neuronal protection - increasing antioxidant defenses Neurogenesis - potentially supporting the formation of new neurons Animal studies have shown that butyrate supplementation is associated with improvements in memory performance and learning ability in preclinical models, especially those simulating aging
Post-secretory fate of host defence components in mucus
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Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials
Additionally, confounding factors such as varying metabolic health statuses of study populations, differences in the duration of obesity, and the presence of comorbidities (e.g., non-alcoholic fatty liver disease) may contribute to divergent secretion patterns
