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GPX3 can use glutathione as an excellent substrate to participate in the redox reactions involved in glutathione and NADPH (Figure 1)

Identification of cathepsin B as a therapeutic target for ferroptosis of macrophage after spinal cord injury

Barriers to initiating treatment may include delayed recognition of obesity as a disease by public health and medical organizations, provider biases regarding patients with obesity, lack of reimbursement leading to out-of-pocket costs to patients, inadequate training of providers, historical safety issues with AOMs, and perceptions of patients and their caregivers regarding the efficacy of AOMs [14,15,16,17]

Nat Rev Mol Cell Biol (2018) 19(5):28196

It is widely underdiagnosed and can cause a myriad of health problems

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