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This observation may be attributable to the very low glutamate affinity of the L_180 class of NAD + -GDH (MSMEG_4699) [29]

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Elevated lactate implies potential mitochondrial dysfunction, with an increased reliance on glycolysis for ATP production (Mathew et al., 2009

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Beyond its involvement in disease-related signaling pathways, ferroptosis is intricately regulated by the metabolism of iron, carbohydrates, and amino acids

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