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In controlled research, intake can be measured directly in preclinical feeding models or indirectly via weight trajectory and satiety related questionnaires in some study designs

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In an embodiment, there is provided a method of providing therapeutic weight loss comprising administering to a human in need thereof an effective dose of one of the above-described compositions

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BRET assays and in vitro quantification of PPAR-responsive genes were performed as described in Supplementary Information 1

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