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Genetic and Biomarker Factors: Personalizing Your Response Profile Individual variation in GLP-1 and GIP receptor genes (GLP1R, GIPR, FTO, MC4R variants) can influence appetite suppression intensity, weight loss trajectory, and optimal medication dose

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Variants in FTO , GLP1R (the receptor every GLP-1 compound targets), MC4R , and TCF7L2 describe the baseline appetite, glucose, and energy-balance biology a clinician prescribes into

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doi: 10.1073/pnas.0506483102 106

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