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No human data exists for ASC35 yet, so a clinical comparison isn't possible

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Contribution statement MA contributed to the generation of the results and analysis using the TriNetX platform and took the lead on writing the manuscript

Mazdutide works by activating two receptors at once: GLP-1, which suppresses appetite and slows gastric emptying, and the glucagon receptor, which increases energy expenditure and supports hepatic fat metabolism

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For all models, we used diagnostic plots (residuals vs fitted and qqplot) to examine assumptions of normality and homogeneity of variances, and we tested uniformity and dispersion of the residuals using the DHARMa package 54