GLP-1 drugs don't cause stones in everyone, but they increase risk in susceptible individuals
I understand the question
00:00:57 Narrator With that, Lets get started 00:01:05 Vickie Danaher We know that the injectable GLP-1 medications have become pretty popular over the last few years for obesity, type 2 diabetes, and other conditions, but the fact that we now have an oral GLP-1 agonist for weight loss is a big change
Betul Hatipoglu, director of the Center for Diabetes, Obesity and Metabolism at Case Western Reserve University and of the Diabetes and Obesity Center at University Hospitals Cleveland Medical Center, says microdosing Ozempic, Zepbound or another GLP-1 drug might mean: Taking a lower dose than what was prescribed or studied in clinical trials Taking a half-dose every few days instead of a full dose once weekly Taking a full dose less often, such as every 10 or 14 days instead of every seven While these approaches are often grouped together online under the umbrella of "microdosing," they're not exactly the same thing
References Abrahami D, DAndrea E, Yin H, Kim SC, Paik JM, Wexler D, et al
They compared exercise alone, exercise plus liraglutide, or liraglutide alone in people without diabetes.[ref] Works even at lower doses: A 2025 study found that people who werent as consistent in taking daily doses or in taking the prescribed amount still had significant weight loss.[ref] 9 Natural supplements and diet changes that increase GLP-1 Access this content: An active subscription is required to access this content