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Selkoe, D

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These findings indicate potential pathways through which incretin therapy may: Stimulate bone formation by activating osteoblasts Inhibit bone resorption via osteoclast suppression Influence calcium and phosphate homeostasis Together, these mechanisms offer biologic plausibility that GLP1 RAs could help preserve bone strength

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There were no new serious or severe adverse reactions identified in this trial

This rationale spurred extensive investigation of diverse probiotic strains during the SARS-CoV-2 pandemic