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10.1007/s11010-015-2430-2 21

The levels of interleukin-1 (IL-1), tumor necrosis factor alpha (TNF-), p38 mitogen-activated protein kinases (p38MAPK), acetylcholine esterase, malondialdehyde (MDA), and nuclear factor kappa B (NF-B) were suppressed, while the brain-derived neurotrophic factor (BDNF) and peroxisome proliferator-activated receptor- (PPAR-) contents were elevated in the brain tissues of AD animals

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Metabolically, the picture looks like this: fasting blood glucose tends to sit in the higher-normal to pre-diabetic range, triglycerides are often elevated, and blood pressure readings are frequently above optimal

Li Y, Lee SH, Piao M, Kim HS, Lee KY