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(2021a) demonstrated that several antidepressant medications exerted a variety of cytotoxic effects on the spermatogenesis pathway in a time- and concentration-dependent manner (escitalopram, 30 M

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For Salviolone, the major potential targeting pathways included Neuroactive ligand-receptor interaction pathway, Calcium signaling pathway, Cholinergic synapse, and Metabolic pathways (Fig

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