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We did not estimate a treatment-policy (all-exposed/intention-to-treat-like) effect, as this represents a different estimand and would require additional prespecified analytic assumptions to appropriately handle treatment modification and its potentially non-random occurrence in routine care

Zero head-to-head comparisons with any approved therapy

Saxenda - for weight management) Exenatide (Byetta, Bydureon - for type 2 diabetes) Lixisenatide (Lyxumia - for type 2 diabetes) These medications are administered either as subcutaneous injections (weekly or daily, depending on the formulation) or as oral tablets (Rybelsus)

TO: Conceptualization, Data curation, Writing review and editing

Results: Our data revealed that Semaglutide administration significantly improved liver function and hepatic steatosis in T2DM combined with NAFLD mice

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