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In addition to the physical symptoms, constipation can also have a psychological impact, leading to feelings of frustration or anxiety about bowel health

Neuroprotective efficacy was evidenced by a 62% reduction in the loss of tyrosine hydroxylase+ neurons in the substantia nigra and substantial recovery of striatal dopamine and metabolites

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Arch Med Res 38:948 Raftos JE, Whillier S, Kuchel PW (2010) Glutathione synthesis and turnover in the human erythrocyte: alignment of a model based on detailed enzyme kinetics with experimental data

The nasal route also offers a direct portal to deliver substances directly into the brain via neuron pathways without being encumbered by the limitations of the blood-brain barrier

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