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Despite the valuable insights gained from this scoping review, several limitations should be acknowledged

Therefore, in the interpretation of semaglutide-related oral adverse effects we integrated indirect evidencefrom transcriptomic datasets, pancreatic and GPCR signaling models, -arrestin biology, and pharmacokinetic behavior

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The drug targets receptors for glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and glucagon, working together to regulate metabolism, appetite and blood sugar levels