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Phentermine should be stopped seven days before planned general anesthesia

10.1152/ajplung.00051.2016 57 ZhangR.BrennanM.ShenZ.MacPhersonJ.SchmittD.MolendaC.et al (2002)

et al., Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity, Nature, 2014

"It looks okay when it's all pulled in, but then I feel like, when I take my clothes off, I look like a 90-year-old woman

Acts as a protective layer to resist UV damage and the destruction of collagen, keeping the skin elastic, prevents sun pigmentation, wrinkles, and premature aging

Insulin resistance is also linked with weight gain and metabolism