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of the CY 2026 OPPS/ASC proposed rule and in this section

B-12 Side Effects B-12 occurs naturally in three forms: methylcobalamin, adenosylcobalamin, and hydroxocobalamin

These components are known as Methionine, Inositol, and Choline

This helps to create a smoother, more uniform appearance

Some commenters who opposed finalizing our proposal agreed with CMS that conceptually a methodology that relies more on market-based concepts would be preferable to the current system of administered pricing, but disagreed that our current proposal was an appropriate approach because they asserted that it risked circular and destabilizing effects across both FFS and MA and could create uncertainty within the MA program, FFS program, and value-based payment models that depend on a stable FFS baseline

[7] In addition, oral contraceptives have been noted to lower serum B levels, though this effect is usually clinically insignificant