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The following adverse reactions are discussed elsewhere: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in clinical trials of a drug cannot be directly compared to rates in the clinical trial of another drug and may not reflect the rates observed in practice

International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use

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Particularly, tumor growth under hypoxia or mitochondrial dysfunction relies almost exclusively on this reductive glutamine metabolism for lipid biosynthesis (Metallo et al., 2011)

The goal of treatment is not just to make the pain go away, but to resolve the underlying issues as well so that the pain doesnt return