Specifically, time-to-on, or a latency from the treatment intake to the patient turning to on-state has been recognized as a major contributor to total daily off-time [11], and SC apomorphine treatment has been shown to rapidly and significantly reduce time-to-on in patients with Parkinsons disease experiencing delayed onset of their morning levodopa dose [29], which is consistent with the present data
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Nomoto A, Omata T, Toyoda H, Kuge S, Horie H, et al
Those with severe organ dysfunction should consult physicians before use
Rapid modulation of the silent information regulator 1 by melatonin after hypoxia-ischemia in the neonatal rat brain
Identification of potential ferroptosis-related biomarkers and immune infiltration in human coronary artery atherosclerosis
