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[1] Adiposity and Microbiome Studies Paired with a low-fat diet, 5-amino-1-methylquinolinium was used to study whole-body adiposity and weight change in DIO mice, moving several measures toward age-matched lean controls within the study window

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The 50100mg range appears in protocols because it approximates allometric scaling from effective rodent doses, but rigorous human pharmacokinetic data validating those numbers is sparse

Scenario 2: Already Lean, Targeting Stubborn Fat Starting point: 80 kg male, 18% body fat, 14.4 kg fat mass