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doi: 10.1016/j.molmet.2024.101880 [DOI] [PMC free article] [PubMed] [Google Scholar] 244

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Researchers who assume short half life equals short effect duration are applying the wrong mental model

Cancer Lett 621:217697 Yao Y, Zhou J, Song J et al (2025) Ruxolitinib enhances gastric cancer to chemotherapy by suppressing JAK/STAT3 and inducing mitochondrial dysfunction and oxidative stress

The GI effects of retatrutide, particularly nausea and reduced appetite, can make it harder to maintain the caloric and protein intake needed to support tissue repair processes