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Unknowns and downsides exist, including potential side effects, high cost, weight regain after stopping the drug, non-response by some people and possible muscle and bone density loss

While semaglutide does not directly increase estrogen, the weight loss it produces can reduce excess aromatase activity and normalize estrogen ratios, particularly in women who are carrying excess visceral fat

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Your physician will recommend a treatment cycle based on your personalized wellness plan, treatment goals, and response to therapy