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Different types of cells have different requirements for ATP, podocytes, endothelial cells and mesangial cells mainly use glucose for their energy supply, while renal tubular cells mainly use free fatty acids, glutamine, pyruvate, citrate and lactate as substrates for fuel supply through aerobic respiration (Scholz et al., 2021)

HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimers disease

Trends Cell Biol 14: 20-28, 2004

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Moreover, the study of iron death in epilepsy treatment is still in the preliminary exploration phase, and there is a lack of systematic clinical trial data