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Conclusion SGLT2 inhibitors are established therapies for reducing HF outcomes, whereas GLP-1 receptor agonists primarily address cardiometabolic risk with uncertain direct HF benefit

What constitutes unresponsive: Clinically, per manufacture, a patient should not be considered as unresponsive to therapy until less than 5% weight loss over the course of 3 months of GLP1/GIP medication at prescribed dose has been established

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The clinic operates on a cash-pay model and doesnt assist with prior authorizations or insurance billing, so all payments are out of pocket

Elife 6 , e24437 (2017)