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156,157 In clinical studies, metformin has been found to significantly minimize the risk of cognitive impairment in T2D

Phase 2 trial data published in the New England Journal of Medicine (2023) demonstrated average reductions in body weight exceeding 20% over 48 weeks in some participants

Its also important to make sure that there will not be any interactions between supplements and medications that could lead to health concerns or change the medicines effectiveness

It is vital to take into account that AOXs should be given in proper dose and duration as excessive intake can lead to reductive stress (171, 172)

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do

In January of 2025, Ozempic was also approved to reduce the risk of kidney disease progression, kidney failure, and death from cardiovascular disease in individuals with chronic kidney disease and type 2 diabetes