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The cells were cultured in normal-glucose medium for 48 h and then treated with the following media: (1) low glucose group (LG) (5.5 mM)

FDA concerns on file include peptide impurities, inadequate characterization, and immunogenicity risk from inconsistent synthesis

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease

Sterile diluent (water + 0.9% benzyl alcohol preservative) Type Sterile diluent (water + 0.9% benzyl alcohol preservative) CAS Number 100-51-6 (benzyl alcohol component) Molecular Weight Amino Acids Sequence Formula H2O + C7H8O (0.9% w/v) Storage & Stability Handling requirements Lyophilized (powder) N/A supplied as sterile solution Reconstituted Use within 28 days of first vial puncture Light Store away from direct light Room temperature Stable at controlled room temperature (15-25C)

Some of the primary genes impacted are COL1A1 (matrix), VEGFA (angiogenesis), IL6 (inflammation), and SOD2 (oxidative defense)