2012 Wolfe RR et al
Cooper DM, Rothstein MA, Amin A, Hirsch JD, Cooper E
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Its utility toward this end was the subject of a 2020 analysis of two clinical trials on individuals with HIV in which the authors concluded, Tesamorelin was effective in increasing skeletal muscle area and density.17 Strength and muscle studies are lacking with regard to non-HIV subjects, but the theoretical efficacy is there
Adding complexity to the study of these receptors, there is extensive species-specificity, so that animal findings result in poorly translatable data, requiring the generation of complex human-murine chimera currently under intense study (305, 306)