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It decreases COX-2 gene expression, reduces myeloperoxidase activity, and lowers pro-inflammatory cytokines including IL-6 and TNF-alpha

For both pretreatment TEE and pretreatment EI, BW gave similarly robust fits alone compared with adding FFM, FM or both, with or without experiment as a covariate

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Front Pharmacol 12:679610 Zilinyi R, Czompa A, Czegledi A, Gajtko A, Pituk D, Lekli I, Tosaki A (2018) The cardioprotective effect of metformin in doxorubicin-induced cardiotoxicity: the role of autophagy