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Next-generation combinations (GLP-1 + GIP, triple agonists with glucagon, GLP-1 + amylin) are even more powerful and represent the future of metabolic therapeutics - potentially 25-30% body weight reduction with profound improvements in liver fat, insulin sensitivity, and cardiovascular markers

Its glucagon activation component can increase the bodys energy output, which is useful for those whose metabolism has slowed

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PA requests for non-preferred hypoglycemics, insulins long-acting drugs may be submitted on the Portal, by fax, or by mail (but not using the STAT-PA system)