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Also, lowering GSH levels in animals has previously been shown to prevent obesity-related phenotypes in mice, such as weight gain under a high-fat diet 79,80

How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test reveals predispositions in key GLP-1 pathway variantsincluding GLP1R rs6923761that may help provide context for individual tolerance patterns

Although the difference did not reach statistical significance, there is a trend toward a difference between %WL since surgery at baseline between groups ( P = 0.061)

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Current clinical trial data shows that GLP-1s lead to significant weight loss (15-20%) after one year of consistent usage