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Participants with renal impairment were excluded if they had previously undergone renal transplantation or had unstable renal function or acute exacerbation of renal disease within 14 days of baseline, as indicated by recent history or worsening of clinical or laboratory signs

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de Haan JB, Bladier C, Griffiths P, Kelner M, OShea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS, et al

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As an antioxidant, glutathione neutralizes free radicalsunstable molecules that can cause inflammation and aging