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For copper peptide research specifically, this study demonstrates that delivering copper peptides directly to the follicle (bypassing the skin barrier through microneedling) produces significantly stronger results than topical application alone

Mechanistically, this phenotype may involve SOCS-dependent pathways

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for 10 min, 25 L of agonist was dispensed into the well using a FlexStation III microplate reader (Molecular Devices), and the intracellular calcium change was recorded at an excitation wavelength of 485 nm and an emission wavelength of 525 nm